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Biological variations of ADAMTS13 and von Willebrand factor in human adults

BACKGROUND: The ultra-large von Willebrand factor (vWF) multimers are very active and must be degraded by ADAMTS13 for optimal activity. A severe functional deficiency of ADAMTS13 has been associated with thrombotic thrombocytopenic purpura. The correct interpretation of patient vWF and ADAMTS13 pla...

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Detalhes bibliográficos
Main Authors: Kilercik, Meltem, Coskun, Abdurrahman, Serteser, Mustafa, Inan, Deniz, Unsal, Ibrahim
Formato: Artigo
Idioma:Inglês
Publicado em: Croatian Society of Medical Biochemistry and Laboratory Medicine 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936977/
https://ncbi.nlm.nih.gov/pubmed/24627722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11613/BM.2014.015
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