Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?

Recently, contradictory findings have been reported concerning the function of irisin and its precursor gene, skeletal muscle FNDC5, in energy homeostasis, and the associated regulatory role of exercise and PGC-1α. We therefore evaluated whether muscle FNDC5 mRNA and serum irisin are exercise respon...

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Bibliographic Details
Main Authors: Pekkala, Satu, Wiklund, Petri K, Hulmi, Juha J, Ahtiainen, Juha P, Horttanainen, Mia, Pöllänen, Eija, Mäkelä, Kari A, Kainulainen, Heikki, Häkkinen, Keijo, Nyman, Kai, Alén, Markku, Herzig, Karl-Heinz, Cheng, Sulin
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2013
Subjects:
Skeletal Muscle and Exercise
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936375/
https://ncbi.nlm.nih.gov/pubmed/24000180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.263707
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