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Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?

Recently, contradictory findings have been reported concerning the function of irisin and its precursor gene, skeletal muscle FNDC5, in energy homeostasis, and the associated regulatory role of exercise and PGC-1α. We therefore evaluated whether muscle FNDC5 mRNA and serum irisin are exercise respon...

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Detalhes bibliográficos
Main Authors: Pekkala, Satu, Wiklund, Petri K, Hulmi, Juha J, Ahtiainen, Juha P, Horttanainen, Mia, Pöllänen, Eija, Mäkelä, Kari A, Kainulainen, Heikki, Häkkinen, Keijo, Nyman, Kai, Alén, Markku, Herzig, Karl-Heinz, Cheng, Sulin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936375/
https://ncbi.nlm.nih.gov/pubmed/24000180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.263707
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