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Progress and Challenges in the Biology of FNDC5 and Irisin
In 2002, a transmembrane protein—now known as FNDC5—was discovered and shown to be expressed in skeletal muscle, heart, and brain. It was virtually ignored for 10 years, until a study in 2012 proposed that, in response to exercise, the ectodomain of skeletal muscle FNDC5 was cleaved, traveled to whi...
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| Publicado no: | Endocr Rev |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284618/ https://ncbi.nlm.nih.gov/pubmed/33493316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endrev/bnab003 |
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