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Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?
FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain. Irisin was proposed to be secreted by skeletal muscle cells in...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774709/ https://ncbi.nlm.nih.gov/pubmed/24052909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adip.26082 |
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