Irisin – a myth rather than an exercise-inducible myokine

The myokine irisin is supposed to be cleaved from a transmembrane precursor, FNDC5 (fibronectin type III domain containing 5), and to mediate beneficial effects of exercise on human metabolism. However, evidence for irisin circulating in blood is largely based on commercial ELISA kits which are base...

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Pubblicato in:Sci Rep
Autori principali: Albrecht, Elke, Norheim, Frode, Thiede, Bernd, Holen, Torgeir, Ohashi, Tomoo, Schering, Lisa, Lee, Sindre, Brenmoehl, Julia, Thomas, Selina, Drevon, Christian A., Erickson, Harold P., Maak, Steffen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352853/
https://ncbi.nlm.nih.gov/pubmed/25749243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08889
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