Irisin – a myth rather than an exercise-inducible myokine

The myokine irisin is supposed to be cleaved from a transmembrane precursor, FNDC5 (fibronectin type III domain containing 5), and to mediate beneficial effects of exercise on human metabolism. However, evidence for irisin circulating in blood is largely based on commercial ELISA kits which are base...

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Vydáno v:Sci Rep
Hlavní autoři: Albrecht, Elke, Norheim, Frode, Thiede, Bernd, Holen, Torgeir, Ohashi, Tomoo, Schering, Lisa, Lee, Sindre, Brenmoehl, Julia, Thomas, Selina, Drevon, Christian A., Erickson, Harold P., Maak, Steffen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352853/
https://ncbi.nlm.nih.gov/pubmed/25749243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08889
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