Prostate Epithelium-Specific Deletion of the Selenocysteine tRNA Gene Trsp Leads to Early Onset Intraepithelial Neoplasia

Although various lines of evidence suggest that oxidative stress plays a role in human prostate cancer initiation and progression, there is a paucity of direct evidence for its role in tumor initiation. To begin to address this issue, we developed a novel tumorigenesis model by reducing the expressi...

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Main Authors: Luchman, H. Artee, Villemaire, Michelle L., Bismar, Tarek A., Carlson, Bradley A., Jirik, Frank R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936312/
https://ncbi.nlm.nih.gov/pubmed/24447801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.11.025
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