Photoaffinity Labeling the Propofol Binding Site in GLIC()

Propofol, an intravenous general anesthetic, produces many of its anesthetic effects in vivo by potentiating the responses of GABA type A receptors (GABA(A)R), members of the superfamily of pentameric ligand-gated ion channels (pLGICs) that contain anion-selective channels. Propofol also inhibits pL...

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Bibliographic Details
Main Authors:	Chiara, David C., Gill, Jonathan F., Chen, Qiang, Tillman, Tommy, Dailey, William P., Eckenhoff, Roderic G., Xu, Yan, Tang, Pei, Cohen, Jonathan B.
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3935609/ https://ncbi.nlm.nih.gov/pubmed/24341978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401492k
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Photoaffinity Labeling the Propofol Binding Site in GLIC()

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