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Photoaffinity labeling in target- and binding-site identification
Photoaffinity labeling (PAL) using a chemical probe to covalently bind its target in response to activation by light has become a frequently used tool in drug discovery for identifying new drug targets and molecular interactions, and for probing the location and structure of binding sites. Methods t...
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| Publié dans: | Future Med Chem |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4413435/ https://ncbi.nlm.nih.gov/pubmed/25686004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.152 |
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