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Identification of alcohol binding site(s) in proteins using diazirine-based photoaffinity labeling and mass spectrometry

Defining molecular targets of alcohol and understanding the molecular mechanism of alcohol actions are necessary to develop effective therapeutics for Alcohol Use Disorder (AUD). Here we describe a detailed protocol for identifying alcohol binding site(s) in proteins using diazirine-based azialcohol...

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Detalles Bibliográficos
Publicado en:Chem Biol Drug Des
Autor Principal: Das, Joydip
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476695/
https://ncbi.nlm.nih.gov/pubmed/30346111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13403
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