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Photoaffinity labeling in target- and binding-site identification

Photoaffinity labeling (PAL) using a chemical probe to covalently bind its target in response to activation by light has become a frequently used tool in drug discovery for identifying new drug targets and molecular interactions, and for probing the location and structure of binding sites. Methods t...

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Vydáno v:Future Med Chem
Hlavní autoři: Smith, Ewan, Collins, Ian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413435/
https://ncbi.nlm.nih.gov/pubmed/25686004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.152
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