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Dysfunction of outer segment guanylate cyclase caused by retinal disease related mutations
Membrane bound guanylate cyclases are expressed in rod and cone cells of the vertebrate retina and mutations in several domains of rod outer segment guanylate cyclase 1 (ROS-GC1 encoded by the gene GUCY2D) correlate with different forms of retinal degenerations. In the present work we investigated t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935488/ https://ncbi.nlm.nih.gov/pubmed/24616660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00004 |
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