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Dysfunction of outer segment guanylate cyclase caused by retinal disease related mutations

Membrane bound guanylate cyclases are expressed in rod and cone cells of the vertebrate retina and mutations in several domains of rod outer segment guanylate cyclase 1 (ROS-GC1 encoded by the gene GUCY2D) correlate with different forms of retinal degenerations. In the present work we investigated t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zägel, Patrick, Koch, Karl-Wilhelm
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935488/
https://ncbi.nlm.nih.gov/pubmed/24616660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00004
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