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HDACs link the DNA damage response, processing of double-strand breaks and autophagy

Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics, protein turnover and the DNA damage response. ATM and ATR mediate DNA damage checkpoints by sensing double-strand breaks and single-strand-DNA–RFA nucleofilaments, respe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Robert, Thomas, Vanoli, Fabio, Chiolo, Irene, Shubassi, Ghadeer, Bernstein, Kara A., Rothstein, Rodney, Botrugno, Oronza A., Parazzoli, Dario, Oldani, Amanda, Minucci, Saverio, Foiani, Marco
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935290/
https://ncbi.nlm.nih.gov/pubmed/21368826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09803
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