HDACs link the DNA damage response, processing of double-strand breaks and autophagy

Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics, protein turnover and the DNA damage response. ATM and ATR mediate DNA damage checkpoints by sensing double-strand breaks and single-strand-DNA–RFA nucleofilaments, respe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Robert, Thomas, Vanoli, Fabio, Chiolo, Irene, Shubassi, Ghadeer, Bernstein, Kara A., Rothstein, Rodney, Botrugno, Oronza A., Parazzoli, Dario, Oldani, Amanda, Minucci, Saverio, Foiani, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935290/
https://ncbi.nlm.nih.gov/pubmed/21368826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09803
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge