HDACs link the DNA damage response, processing of double-strand breaks and autophagy

Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics, protein turnover and the DNA damage response. ATM and ATR mediate DNA damage checkpoints by sensing double-strand breaks and single-strand-DNA–RFA nucleofilaments, respe...

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Autores principales: Robert, Thomas, Vanoli, Fabio, Chiolo, Irene, Shubassi, Ghadeer, Bernstein, Kara A., Rothstein, Rodney, Botrugno, Oronza A., Parazzoli, Dario, Oldani, Amanda, Minucci, Saverio, Foiani, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935290/
https://ncbi.nlm.nih.gov/pubmed/21368826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09803
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