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Selective constraint in protein polymorphism: Study of the effectively neutral mutation model by using an improved pseudosampling method

To investigate the pattern of allelic distribution in enzyme polymorphism, with special reference to the relationship between the mean (H) and the variance (V(H)) of heterozygosity, we used the model of effectively neutral mutations involving multiple alleles in which selective disadvantage of mutan...

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Detalhes bibliográficos
Main Authors: Kimura, Motoo, Takahata, Naoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC393525/
https://ncbi.nlm.nih.gov/pubmed/6573657
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