Selective constraint in protein polymorphism: Study of the effectively neutral mutation model by using an improved pseudosampling method
To investigate the pattern of allelic distribution in enzyme polymorphism, with special reference to the relationship between the mean (H) and the variance (V(H)) of heterozygosity, we used the model of effectively neutral mutations involving multiple alleles in which selective disadvantage of mutan...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1983
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6573657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.1048 |
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