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Average time until fixation of a mutant allele in a finite population under continued mutation pressure: Studies by analytical, numerical, and pseudo-sampling methods

We consider a single locus, and denote by A the wild-type allele and by A′ the mutant allele that is produced irreversibly in each generation from A at the rate v. Let 1 + s, 1 + h, and 1 be, respectively, the relative fitnesses of mutant homozygote A′A′, mutant heterozygote A′A, and wild-type homoz...

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Veröffentlicht in:Proc Natl Acad Sci U S A
1. Verfasser: Kimura, Motoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1980
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.522
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