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Average time until fixation of a mutant allele in a finite population under continued mutation pressure: Studies by analytical, numerical, and pseudo-sampling methods

We consider a single locus, and denote by A the wild-type allele and by A′ the mutant allele that is produced irreversibly in each generation from A at the rate v. Let 1 + s, 1 + h, and 1 be, respectively, the relative fitnesses of mutant homozygote A′A′, mutant heterozygote A′A, and wild-type homoz...

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Autore principale: Kimura, Motoo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC348304/
https://ncbi.nlm.nih.gov/pubmed/16592764
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