Average time until fixation of a mutant allele in a finite population under continued mutation pressure: Studies by analytical, numerical, and pseudo-sampling methods
We consider a single locus, and denote by A the wild-type allele and by A′ the mutant allele that is produced irreversibly in each generation from A at the rate v. Let 1 + s, 1 + h, and 1 be, respectively, the relative fitnesses of mutant homozygote A′A′, mutant heterozygote A′A, and wild-type homoz...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1980
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592764/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.522 |
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