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Selective constraint in protein polymorphism: Study of the effectively neutral mutation model by using an improved pseudosampling method

To investigate the pattern of allelic distribution in enzyme polymorphism, with special reference to the relationship between the mean (H) and the variance (V(H)) of heterozygosity, we used the model of effectively neutral mutations involving multiple alleles in which selective disadvantage of mutan...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kimura, Motoo, Takahata, Naoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393525/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6573657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.1048
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