Učitavanje...
Regulation of β(2)-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
The biologic activity induced by ligand binding to orthosteric or allosteric sites on a G protein–coupled receptor (GPCR) is mediated by stabilization of specific receptor conformations. In the case of the β(2) adrenergic receptor, these ligands are generally small-molecule agonists or antagonists....
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Glavni autori: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935154/ https://ncbi.nlm.nih.gov/pubmed/24319111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.089516 |
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