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An Intrabody Based on a Llama Single-domain Antibody Targeting the N-terminal α-Helical Multimerization Domain of HIV-1 Rev Prevents Viral Production

The human immunodeficiency virus, type 1 (HIV-1)-encoded Rev protein is essential for the expression of late viral mRNAs. Rev forms a large organized multimeric protein-protein complex on the Rev response element of these viral mRNA species and transports them from the nucleus to the cytoplasm, expl...

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Bibliografische gegevens
Hoofdauteurs: Vercruysse, Thomas, Pardon, Els, Vanstreels, Els, Steyaert, Jan, Daelemans, Dirk
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898381/
https://ncbi.nlm.nih.gov/pubmed/20406803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112490
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