Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev

HIV-1 Rev is the key protein in the nucleocytoplasmic export and expression of the late viral mRNAs. An important aspect for its function is its ability to multimerize on these mRNAs. We have recently identified a llama single-domain antibody (Nb(190)) as the first inhibitor targeting the Rev multim...

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Detalhes bibliográficos
Main Authors: Vercruysse, Thomas, Boons, Eline, Venken, Tom, Vanstreels, Els, Voet, Arnout, Steyaert, Jan, De Maeyer, Marc, Daelemans, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615019/
https://ncbi.nlm.nih.gov/pubmed/23565213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060259
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