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Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev

HIV-1 Rev is the key protein in the nucleocytoplasmic export and expression of the late viral mRNAs. An important aspect for its function is its ability to multimerize on these mRNAs. We have recently identified a llama single-domain antibody (Nb(190)) as the first inhibitor targeting the Rev multim...

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Main Authors: Vercruysse, Thomas, Boons, Eline, Venken, Tom, Vanstreels, Els, Voet, Arnout, Steyaert, Jan, De Maeyer, Marc, Daelemans, Dirk
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615019/
https://ncbi.nlm.nih.gov/pubmed/23565213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060259
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