Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer

The export of viral RNA from the nucleus to the cytoplasm of the cellular host is a crucial step in the life cycle of HIV-1 that is mediated by the viral Rev protein. One aspect of the Rev function, its multimerization, is still unexplored as a target for antiviral therapy. This is partly due to the...

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Main Authors: Vercruysse, Thomas, Pawar, Sonalika, De Borggraeve, Wim, Pardon, Els, Pavlakis, George N, Pannecouque, Christophe, Steyaert, Jan, Balzarini, Jan, Daelemans, Dirk
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2011
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127102/
https://ncbi.nlm.nih.gov/pubmed/21358282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.2.13782
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