A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

BACKGROUND: Sexual acquisition of the human immunodeficiency virus (HIV) through mucosal transmission may be prevented by using topically applied agents that block HIV transmission from one individual to another. Therefore, virucidal agents that inactivate HIV virions may be used as a component in t...

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Main Authors: Vercruysse, Thomas, Basta, Beata, Dehaen, Wim, Humbert, Nicolas, Balzarini, Jan, Debaene, François, Sanglier-Cianférani, Sarah, Pannecouque, Christophe, Mély, Yves, Daelemans, Dirk
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542062/
https://ncbi.nlm.nih.gov/pubmed/23146561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-95
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