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Production, crystallization and preliminary X-ray diffraction of the Gαs α-helical domain in complex with a nanobody
GPCR–G-protein complexes are one of the most important components of cell-signalling cascades. Extracellular signals are sensed by membrane-associated G-protein-coupled receptors (GPCRs) and transduced via G proteins towards intracellular effector molecules. Structural studies of these transient com...
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| Veröffentlicht in: | Acta Crystallogr F Struct Biol Commun |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231852/ https://ncbi.nlm.nih.gov/pubmed/25372817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14020962 |
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