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Excitotoxic glutamate insults block autophagic flux in hippocampal neurons

Excitotoxic insults such as cerebral ischemia are thought to enhance neuronal autophagy, which is then thought to promote neuronal cell death. Excitotoxic insults indeed increase autophagy markers. Notably, however, autophagy markers can be increased either by autophagy induction (as this enhances t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kulbe, Jacqueline R., Mulcahy Levy, Jean M., Coultrap, Steven J., Thorburn, Andrew, Bayer, K. Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934833/
https://ncbi.nlm.nih.gov/pubmed/24505621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.10.032
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