Apnea promotes glutamate-induced excitotoxicity in hippocampal neurons

Patients with obstructive sleep apnea (OSA) exhibit hippocampal damage and cognitive deficits. To determine the effect of apnea on the synaptic transmission in the hippocampus, we performed electrophysiological studies in an in vivo guinea pig model of OSA. Specifically, we determined the cornu ammo...

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Main Authors: Fung, Simon J., Xi, Ming-Chu, Zhang, Jian-Hua, Sampogna, Sharon, Yamuy, Jack, Morales, Francisco R., Chase, Michael H.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169175/
https://ncbi.nlm.nih.gov/pubmed/17888415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.08.044
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