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Excitotoxic glutamate insults block autophagic flux in hippocampal neurons

Excitotoxic insults such as cerebral ischemia are thought to enhance neuronal autophagy, which is then thought to promote neuronal cell death. Excitotoxic insults indeed increase autophagy markers. Notably, however, autophagy markers can be increased either by autophagy induction (as this enhances t...

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Detalles Bibliográficos
Main Authors: Kulbe, Jacqueline R., Mulcahy Levy, Jean M., Coultrap, Steven J., Thorburn, Andrew, Bayer, K. Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934833/
https://ncbi.nlm.nih.gov/pubmed/24505621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.10.032
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