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Mapping the Kinetic Barriers of a Large RNA Molecule's Folding Landscape

The folding of linear polymers into discrete three-dimensional structures is often required for biological function. The formation of long-lived intermediates is a hallmark of the folding of large RNA molecules due to the ruggedness of their energy landscapes. The precise thermodynamic nature of the...

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Detalhes bibliográficos
Main Authors: Schlatterer, Jörg C., Martin, Joshua S., Laederach, Alain, Brenowitz, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934814/
https://ncbi.nlm.nih.gov/pubmed/24586236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085041
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