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Complementing global measures of RNA folding with local reports of backbone solvent accessibility by time resolved hydroxyl radical footprinting
A variety of analytical techniques are used to probe the mechanisms by which RNA molecules fold to discrete three dimensional structures. Methods such as small angle X-ray scattering (SAXS) report global properties such as the overall size and shape of the RNA. Other methods such as chemical or enzy...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753680/ https://ncbi.nlm.nih.gov/pubmed/19426806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.04.019 |
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