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Complementing global measures of RNA folding with local reports of backbone solvent accessibility by time resolved hydroxyl radical footprinting
A variety of analytical techniques are used to probe the mechanisms by which RNA molecules fold to discrete three dimensional structures. Methods such as small angle X-ray scattering (SAXS) report global properties such as the overall size and shape of the RNA. Other methods such as chemical or enzy...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753680/ https://ncbi.nlm.nih.gov/pubmed/19426806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.04.019 |
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