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Complementing global measures of RNA folding with local reports of backbone solvent accessibility by time resolved hydroxyl radical footprinting

A variety of analytical techniques are used to probe the mechanisms by which RNA molecules fold to discrete three dimensional structures. Methods such as small angle X-ray scattering (SAXS) report global properties such as the overall size and shape of the RNA. Other methods such as chemical or enzy...

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Detalhes bibliográficos
Main Authors: Schlatterer, Jörg C., Brenowitz, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753680/
https://ncbi.nlm.nih.gov/pubmed/19426806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.04.019
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