IL-17 Gene Ablation Does Not Impact Treg-Mediated Suppression of Graft-Versus-Host Disease after Bone Marrow Transplantation

Regulatory T cell (Treg) immunotherapy is a promising strategy for the treatment of graft rejection responses and autoimmune disorders. Our and other laboratories have shown that the transfer of highly purified CD4(+)CD25(+)Foxp3(+) natural Treg can prevent lethal graft-versus-host disease (GVHD) af...

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Autores principales: Colonna, Lucrezia, Florek, Mareike, Leveson-Gower, Dennis B., Sega, Emanuela I., Baker, Jeanette, Smith, Aaron T., Negrin, Robert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934793/
https://ncbi.nlm.nih.gov/pubmed/23921175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.07.024
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