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Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4–dependent mechanism
CD4(+) natural killer T (NKT) cells, along with CD4(+)CD25(+) regulatory T cells (Tregs), are capable of controlling aberrant immune reactions. We explored the adoptive transfer of highly purified (> 95%) CD4(+)NKT cells in a murine model of allogeneic hematopoietic cell transplantation (HCT). NK...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317770/ https://ncbi.nlm.nih.gov/pubmed/21258007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-303008 |
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