Lipopolysaccharide Stimulates p62-Dependent Autophagy-Like Aggregate Clearance in Hepatocytes

Impairment of autophagy has been associated with liver injury. TLR4-stimulation by LPS upregulates autophagy in hepatocytes, although the signaling pathways involved remain elusive. The objective of this study was to determine the signaling pathway leading to LPS-stimulated autophagy in hepatocytes....

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Hlavní autoři: Chen, Christine, Deng, Meihong, Sun, Qian, Loughran, Patricia, Billiar, Timothy R., Scott, Melanie J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934718/
https://ncbi.nlm.nih.gov/pubmed/24683544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/267350
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