Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha.
The Chinese hamster V79 cell mutant aphr-4-2, selected for its resistance to aphidicolin, a specific inhibitor of DNA polymerase alpha (DNA nucleotidyltransferase, EC 2.7.7.7), is characterized by slow growth, UV sensitivity, and hypersensitivity to UV-induced mutation. DNA polymerase alpha has been...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1983
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6402775/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.3.797 |
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