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Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha.

The Chinese hamster V79 cell mutant aphr-4-2, selected for its resistance to aphidicolin, a specific inhibitor of DNA polymerase alpha (DNA nucleotidyltransferase, EC 2.7.7.7), is characterized by slow growth, UV sensitivity, and hypersensitivity to UV-induced mutation. DNA polymerase alpha has been...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Liu, P K, Chang, C C, Trosko, J E, Dube, D K, Martin, G M, Loeb, L A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6402775/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.3.797
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