Wird geladen...
Discovery of New Liver X Receptor Agonists by Pharmacophore Modeling and Shape-Based Virtual Screening
[Image: see text] Agonists of liver X receptors (LXR) α and β are important regulators of cholesterol metabolism, but agonism of the LXRα subtype appears to cause hepatic lipogenesis, suggesting LXRβ-selective activators are attractive new lipid lowering drugs. In this work, pharmacophore modeling a...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2014
|
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934620/ https://ncbi.nlm.nih.gov/pubmed/24502802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci400682b |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|