ZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats

AIM: To investigate the effects of ZD 7288, a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker, on rats with chronic visceral pain. METHODS: Rats with visceral hypersensitivity were generated using neonatal colon irritation during postnatal days 8-15 as described previously....

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Bibliografiske detaljer
Main Authors: Chen, Yu, Lin, Chun, Tang, Ying, Chen, Ai-Qin, Liu, Cui-Ying, Lu, Da-Li
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Co., Limited 2014
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Brief Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934480/
https://ncbi.nlm.nih.gov/pubmed/24587682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i8.2091
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