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The HCN Channel Blocker ZD7288 Induces Emesis in the Least Shrew (Cryptotis parva)

Subtypes (1–4) of the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in the central and peripheral nervous systems, as well as the cells of smooth muscles in many organs. They mainly serve to regulate cellular excitability in these tissues. The HCN channel bl...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhong, W., Darmani, N. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117105/
https://ncbi.nlm.nih.gov/pubmed/33995059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.647021
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