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ZD7288, a blocker of the HCN channel family, increases doubling time of mouse embryonic stem cells and modulates differentiation outcomes in a context-dependent manner

Pluripotent stem cells are the starting cell type of choice for the development of many cell-based regenerative therapies due to their rapid and unlimited proliferation and broad differentiation potential. The unique pluripotent cell cycle underlies both these properties. Hyperpolarization-activated...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Omelyanenko, Anna, Sekyrova, Petra, Andäng, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715829/
https://ncbi.nlm.nih.gov/pubmed/26835223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-1678-7
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