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Novel Targeting of Phoshatidylinositol-3 Kinase and Mammalian Target of Rapamycin (mTOR) in Renal Cell Carcinoma
Allosteric inhibitors of the kinase mammalian target of rapamycin (mTOR) have demonstrated significant clinical activity in patients with advanced renal cell carcinoma (RCC). Unfortunately, substantial clinical responses to these rapalogues are only seen in a subset of patients with advanced RCC. Pr...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934425/ https://ncbi.nlm.nih.gov/pubmed/23867512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e31829d5cea |
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