Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer

BACKGROUND: PI3K and mTOR are key components of signal transduction pathways critical for cell survival. Numerous PI3K inhibitors have entered clinical trials, while mTOR is the target of approved drugs for metastatic renal cell carcinoma (RCC). We characterized expression of p85 and p110α PI3K subu...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Elfiky, Aymen A, Aziz, Saadia A, Conrad, Patricia J, Siddiqui, Summar, Hackl, Wolfgang, Maira, Michel, Robert, Camp L, Kluger, Harriet M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173341/
https://ncbi.nlm.nih.gov/pubmed/21834980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-133
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky