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Novel Targeting of Phoshatidylinositol-3 Kinase and Mammalian Target of Rapamycin (mTOR) in Renal Cell Carcinoma

Allosteric inhibitors of the kinase mammalian target of rapamycin (mTOR) have demonstrated significant clinical activity in patients with advanced renal cell carcinoma (RCC). Unfortunately, substantial clinical responses to these rapalogues are only seen in a subset of patients with advanced RCC. Pr...

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Bibliografiske detaljer
Hovedforfatter: Cho, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934425/
https://ncbi.nlm.nih.gov/pubmed/23867512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e31829d5cea
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