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Novel Targeting of Phoshatidylinositol-3 Kinase and Mammalian Target of Rapamycin (mTOR) in Renal Cell Carcinoma
Allosteric inhibitors of the kinase mammalian target of rapamycin (mTOR) have demonstrated significant clinical activity in patients with advanced renal cell carcinoma (RCC). Unfortunately, substantial clinical responses to these rapalogues are only seen in a subset of patients with advanced RCC. Pr...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934425/ https://ncbi.nlm.nih.gov/pubmed/23867512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e31829d5cea |
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