Mutant p53–associated myosin-X upregulation promotes breast cancer invasion and metastasis

Mutations of the tumor suppressor TP53 are present in many forms of human cancer and are associated with increased tumor cell invasion and metastasis. Several mechanisms have been identified for promoting dissemination of cancer cells with TP53 mutations, including increased targeting of integrins t...

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Autores principales: Arjonen, Antti, Kaukonen, Riina, Mattila, Elina, Rouhi, Pegah, Högnäs, Gunilla, Sihto, Harri, Miller, Bryan W., Morton, Jennifer P., Bucher, Elmar, Taimen, Pekka, Virtakoivu, Reetta, Cao, Yihai, Sansom, Owen J., Joensuu, Heikki, Ivaska, Johanna
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934176/
https://ncbi.nlm.nih.gov/pubmed/24487586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67280
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