Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription

Tissue homeostasis is dependent on the controlled localization of specific cell types and the correct composition of the extracellular stroma. While the role of the cancer stroma in tumour progression has been well characterized, the specific contribution of the matrix itself is unknown. Furthermore...

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Publicado no:Nat Commun
Main Authors: Kaukonen, Riina, Mai, Anja, Georgiadou, Maria, Saari, Markku, De Franceschi, Nicola, Betz, Timo, Sihto, Harri, Ventelä, Sami, Elo, Laura, Jokitalo, Eija, Westermarck, Jukka, Kellokumpu-Lehtinen, Pirkko-Liisa, Joensuu, Heikki, Grenman, Reidar, Ivaska, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976218/
https://ncbi.nlm.nih.gov/pubmed/27488962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12237
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