Mutant p53–associated myosin-X upregulation promotes breast cancer invasion and metastasis

Mutations of the tumor suppressor TP53 are present in many forms of human cancer and are associated with increased tumor cell invasion and metastasis. Several mechanisms have been identified for promoting dissemination of cancer cells with TP53 mutations, including increased targeting of integrins t...

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Main Authors: Arjonen, Antti, Kaukonen, Riina, Mattila, Elina, Rouhi, Pegah, Högnäs, Gunilla, Sihto, Harri, Miller, Bryan W., Morton, Jennifer P., Bucher, Elmar, Taimen, Pekka, Virtakoivu, Reetta, Cao, Yihai, Sansom, Owen J., Joensuu, Heikki, Ivaska, Johanna
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934176/
https://ncbi.nlm.nih.gov/pubmed/24487586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67280
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