Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models

To examine the role of orexin-1 and orexin-2 receptor activity on ethanol self-administration, compounds that differentially target orexin (OX) receptor subtypes were assessed in various self-administration paradigms using high-drinking rodent models. Effects of the OX(1) antagonist SB334867, the OX...

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Detalhes bibliográficos
Main Authors: Anderson, Rachel I., Becker, Howard C., Adams, Benjamin L., Jesudason, Cynthia D., Rorick-Kehn, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933945/
https://ncbi.nlm.nih.gov/pubmed/24616657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00033
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