Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
We describe a novel approach to assay the ability of particular gene products to signal transitions in lymphocyte differentiation in vivo. The method involves transfection of test expression constructs into RAG-1-deficient embryonic stem cells, which are subsequently assayed by the RAG-2-deficient b...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1996
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643464/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4683 |
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